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24px;position:absolute;inset:0;-webkit-mask-image:radial-gradient(#000 50%,#0000 85%);mask-image:radial-gradient(#000 50%,#0000 85%)}.bg-warm-section{background:radial-gradient(ellipse 60% 50% at 20% 80%,#2a7d4f08 0%,transparent 50%),radial-gradient(ellipse 50% 40% at 80% 20%,#c4501a05 0%,transparent 50%),var(--color-bg-alt)}.noise-overlay:after{content:"";opacity:.025;pointer-events:none;background-image:url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='200' height='200'%3E%3Cfilter id='n'%3E%3CfeTurbulence type='fractalNoise' baseFrequency='0.65' numOctaves='3' stitchTiles='stitch'/%3E%3C/filter%3E%3Crect width='100%25' height='100%25' filter='url(%23n)'/%3E%3C/svg%3E");position:absolute;inset:0}.condition-tile{border:1.5px solid var(--color-border-strong);border-left:3px solid var(--color-hope);border-radius:var(--radius-sm);text-align:left;background:#fff;flex-direction:column;gap:.1875rem;padding:.875rem 1rem;text-decoration:none;transition:transform .25s,box-shadow .25s,border-color .25s,background .25s;display:flex;box-shadow:0 1px 3px #1c2b3a0a}.condition-tile:hover{border-left-color:var(--color-accent);background:var(--color-accent-light);transform:translateY(-2px);box-shadow:0 4px 16px #c4501a1a}.condition-tile:hover .condition-tile-name{color:var(--color-accent-dark)}.condition-tile .condition-tile-count{font-variant-numeric:tabular-nums}.info-card{border:1.5px solid var(--color-border-strong);border-radius:var(--radius-lg);text-align:center;background:#fff;padding:2.25rem 1.75rem;transition:box-shadow .3s,transform .3s,border-color .3s;box-shadow:0 1px 3px #1c2b3a0a,0 4px 12px #1c2b3a08}.info-card:hover{border-color:#1c2b3a33;transform:translateY(-4px);box-shadow:0 4px 12px #1c2b3a0f,0 12px 36px #1c2b3a0d}.info-card-icon{border-radius:50%;justify-content:center;align-items:center;width:60px;height:60px;margin:0 auto 1.25rem;display:flex;box-shadow:0 2px 8px #0000000f}@keyframes fade-up{0%{opacity:0;transform:translateY(20px)}to{opacity:1;transform:translateY(0)}}.fade-up{animation:.6s ease-out both fade-up}.stagger-child{animation-delay:calc(var(--i,0) * .1s)}.scroll-fade{opacity:0;transition:opacity .6s ease-out,transform .6s ease-out;transform:translateY(20px)}.scroll-fade.visible{opacity:1;transform:translateY(0)}@media(prefers-reduced-motion:reduce){.fade-up,.scroll-fade{opacity:1;animation:none;transform:none}.badge-recruiting:before{animation:none}}.search-input{border:2px solid var(--color-border-strong);border-radius:var(--radius-md);font-family:var(--font-body);background:#fff;transition:border-color .2s,box-shadow .2s;box-shadow:0 2px 4px #1c2b3a0a,0 4px 12px #1c2b3a08}.search-input:focus{border-color:var(--color-accent);box-shadow:0 2px 4px #1c2b3a0a,0 0 0 4px var(--color-accent-light);outline:none}.search-input::placeholder{color:var(--color-text-light);font-size:.9375rem}.category-heading{font-family:var(--font-body);text-transform:uppercase;letter-spacing:.08em;color:var(--color-text-muted);border-bottom:1px solid var(--color-border);align-items:center;gap:.5rem;margin-bottom:.75rem;padding-bottom:.5rem;font-size:.75rem;font-weight:700;display:flex}.category-heading:before{content:"";background:var(--color-hope);border-radius:2px;flex-shrink:0;width:8px;height:8px}.stats-bar{border:1.5px solid var(--color-border-strong);color:var(--color-text-muted);background:#fff;border-radius:999px;align-items:center;gap:.75rem;padding:.5rem 1.5rem;font-size:.8125rem;font-weight:500;display:inline-flex;box-shadow:0 1px 4px #1c2b3a0a}.stats-bar .stats-dot{background:var(--color-hope);opacity:.6;border-radius:50%;width:4px;height:4px}.grid-conditions{grid-template-columns:repeat(2,1fr);gap:.75rem;display:grid}@media(min-width:640px){.grid-conditions{grid-template-columns:repeat(3,1fr);gap:.875rem}}@media(min-width:1024px){.grid-conditions{grid-template-columns:repeat(4,1fr)}}.trial-meta{color:var(--color-text-muted);flex-wrap:wrap;gap:.5rem 1.5rem;font-size:.9375rem;display:flex}.trial-meta dt{color:var(--color-text);font-weight:600}.trial-meta dd{margin:0}.skip-link{background:var(--color-accent);color:#fff;border-radius:var(--radius-sm);z-index:100;padding:.75rem 1.25rem;font-weight:600;text-decoration:none;position:absolute;top:-100%;left:1rem}.skip-link:focus{top:1rem}.section-divider{background:linear-gradient(90deg,transparent 0%,var(--color-border-strong) 20%,var(--color-border-strong) 80%,transparent 100%);border:none;height:1px;margin:0}@property --tw-rotate-x{syntax:"*";inherits:false}@property --tw-rotate-y{syntax:"*";inherits:false}@property --tw-rotate-z{syntax:"*";inherits:false}@property --tw-skew-x{syntax:"*";inherits:false}@property --tw-skew-y{syntax:"*";inherits:false}@property --tw-space-y-reverse{syntax:"*";inherits:false;initial-value:0}@property --tw-border-style{syntax:"*";inherits:false;initial-value:solid}@property --tw-font-weight{syntax:"*";inherits:false}@property --tw-tracking{syntax:"*";inherits:false}@property --tw-outline-style{syntax:"*";inherits:false;initial-value:solid}@property --tw-blur{syntax:"*";inherits:false}@property --tw-brightness{syntax:"*";inherits:false}@property --tw-contrast{syntax:"*";inherits:false}@property --tw-grayscale{syntax:"*";inherits:false}@property --tw-hue-rotate{syntax:"*";inherits:false}@property --tw-invert{syntax:"*";inherits:false}@property --tw-opacity{syntax:"*";inherits:false}@property --tw-saturate{syntax:"*";inherits:false}@property --tw-sepia{syntax:"*";inherits:false}@property --tw-drop-shadow{syntax:"*";inherits:false}@property --tw-drop-shadow-color{syntax:"*";inherits:false}@property --tw-drop-shadow-alpha{syntax:"<percentage>";inherits:false;initial-value:100%}@property --tw-drop-shadow-size{syntax:"*";inherits:false}details[data-astro-cid-3ef6ksr2] summary[data-astro-cid-3ef6ksr2]::-webkit-details-marker{display:none}details[data-astro-cid-3ef6ksr2][open] summary[data-astro-cid-3ef6ksr2] svg[data-astro-cid-3ef6ksr2] line[data-astro-cid-3ef6ksr2]:nth-child(1){transform:rotate(45deg) translate(5px,-3px)}details[data-astro-cid-3ef6ksr2][open] summary[data-astro-cid-3ef6ksr2] svg[data-astro-cid-3ef6ksr2] line[data-astro-cid-3ef6ksr2]:nth-child(2){opacity:0}details[data-astro-cid-3ef6ksr2][open] summary[data-astro-cid-3ef6ksr2] svg[data-astro-cid-3ef6ksr2] line[data-astro-cid-3ef6ksr2]:nth-child(3){transform:rotate(-45deg) translate(5px,3px)}nav[data-astro-cid-3ef6ksr2] a[data-astro-cid-3ef6ksr2]:hover{color:var(--color-accent)!important}footer[data-astro-cid-sz7xmlte] a[data-astro-cid-sz7xmlte]:hover{color:var(--color-accent)!important;text-decoration:underline!important}