IRB — What It Means in Clinical Trials
Plain English Definition
An IRB (Institutional Review Board) is an independent committee that reviews and approves clinical trial plans to make sure participants are protected. The IRB includes doctors, scientists, and community members who are not involved in the trial. Every trial must be approved by an IRB before it can begin enrolling participants.
Why It Matters
The IRB is your advocate. They review the trial design, consent forms, and safety plans before anyone can join. If you have concerns about a trial, you can contact the IRB directly — their information is on your consent form.
Example
Your consent form will include a statement like: "This study has been reviewed and approved by the ABC University Institutional Review Board."
Need help understanding eligibility criteria?
How to Read Eligibility Criteria →